Imbalances of other steroids, including cortisol and DHEA, develop as cells compensate for pregnenolone deficiency
1 Argument
0 Citations
1 Consequence
2 Mentions
Arguments
Argument #8a3e83ec 1 0 2
If it is true that...
Estrogen is a brain excitant, present use creates an effect on verbal fluency and other signs of awareness of the environment 1 0 2and
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs 1 0 2Then it must be true that...
Imbalances of other steroids, including cortisol and DHEA, develop as cells compensate for pregnenolone deficiency 1 0 2Opposing Arguments
No opposing arguments found
Citations
No citations found
Consequences
Argument #94643c27 1 0 2
If it is true that...
Imbalances of other steroids, including cortisol and DHEA, develop as cells compensate for pregnenolone deficiency 1 0 2and
Hypothyroidism, estrogen excess, free unsaturated fats cause increased vascular permeability and brain edema, protein leakage, and alteration of the matrix 1 0 2Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs 1 0 2Mentions
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Related Propositions
In old age, the catabolic hormones such as cortisol are relatively dominant 1 0 2Progesterone and pregnenolone, by reducing the stress reactions, should be helpful in the eye diseases of infancy and old age, as they are in the respiratory distress syndromes 1 0 1Cholesterol, pregnenolone, and progesterone are the main long-range defenses in the human body 1 0 2To produce pregnenolone, thyroid, vitamin A, and cholesterol have to be delivered to the mitochondria in the right proportion and sufficient quantity 1 0 2Stress is normally balanced by increased synthesis of pregnenolone, which improves the ability to cope with stress 1 0 2Lipid peroxidation damages the mitochondrias' ability to produce pregnenolone 1 0 2When pregnenolone is inadequate, cortisol is over-produced 1 0 2When progesterone is deficient, estrogen's effect is largely unopposed 1 0 2Increased cortisol and DHEA are associated with Alzheimer's disease 1 0 1Pregnenolone and progesterone deficiency causes memory loss, destabilization of nerve cells, failure of myelin formation, and excess cortisol synthesis 1 0 2