Progesterone and pregnenolone, by reducing the stress reactions, should be helpful in the eye diseases of infancy and old age, as they are in the respiratory distress syndromes
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Progesterone, by increasing oxidative efficiency, opposes this "angiogenic" (neovascularization) effect of estrogen 1 0 2Progesterone is both an anticatabolic hormone and an antiestrogenic hormone, protecting the functional systems from atrophy 1 0 2Progesterone is probably the most perfect antiestrogenic hormone, and therefore an anti-stress and anti-aging hormone 1 0 2Stress, a "respiratory defect", and free radical damage are common factors in disease and aging 1 0 2The retina becomes easier to injure by light in old age for some of the same reasons that the infant's retina is susceptible 1 0 2Synthetic glucocorticoids are often given to premature babies, adding to the risk of retinal damage 1 0 2The use of synthetic glucocorticoid hormone is standard in treating very premature babies although it is known to contribute to eye damage 1 0 2Medical treatments for respiratory distress and macular degeneration in old people are often similar to those used for babies 1 0 1Stress is normally balanced by increased synthesis of pregnenolone, which improves the ability to cope with stress 1 0 2Pregnenolone and progesterone deficiency causes memory loss, destabilization of nerve cells, failure of myelin formation, and excess cortisol synthesis 1 0 2