Lipid peroxidation damages the mitochondrias' ability to produce pregnenolone
Negation: Lipid peroxidation does not damage the mitochondrias' ability to produce pregnenolone 0 0 0
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2 Consequences
2 Mentions
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Argument #52b50dd0 1 0 2
If it is true that...
To produce pregnenolone, thyroid, vitamin A, and cholesterol have to be delivered to the mitochondria in the right proportion and sufficient quantity 1 0 2and
Lipid peroxidation damages the mitochondrias' ability to produce pregnenolone 1 0 2Then it must be true that...
When pregnenolone is inadequate, cortisol is over-produced 1 0 2Argument #c243771f 1 0 2
If it is true that...
Lipid peroxidation damages the mitochondrias' ability to produce pregnenolone 1 0 2Then it must be true that...
When pregnenolone is inadequate, cortisol is over-produced 1 0 2Mentions
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Related Propositions
Estrogen steals oxygen from mitochondria, shifting patterns of growth and adaptation 1 0 2Mitochondrial function in general is poisoned by the unsaturated fats, especially arachidonic acid and DHA 1 0 2Endotoxin impairs mitochondria, increases estrogen levels, causes Kupffer cells in the liver to produce more tumor necrosis factor 1 0 2Cholesterol, pregnenolone, and progesterone are the main long-range defenses in the human body 1 0 2To produce pregnenolone, thyroid, vitamin A, and cholesterol have to be delivered to the mitochondria in the right proportion and sufficient quantity 1 0 2Stress is normally balanced by increased synthesis of pregnenolone, which improves the ability to cope with stress 1 0 2When pregnenolone is inadequate, cortisol is over-produced 1 0 2Apoe, in cytoplasm, is involved in cholesterol delivery for pregnenolone synthesis 1 0 1Pregnenolone and progesterone deficiency causes memory loss, destabilization of nerve cells, failure of myelin formation, and excess cortisol synthesis 1 0 2Imbalances of other steroids, including cortisol and DHEA, develop as cells compensate for pregnenolone deficiency 1 0 2