Estrogen creates an oxygen deficiency, stimulates first swelling, and then collagen synthesis
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Argument #151de20d 1 0 2
If it is true that...
Estrogen is closely associated with the general loss of fat-free tissue with aging 1 0 2and
Estrogen creates an oxygen deficiency, stimulates first swelling, and then collagen synthesis 1 0 2and
Collagen tends to accumulate with aging 1 0 2Then it must be true that...
Estrogen increases the blood flow to particular organs, but apparently less than it increases their oxygen demand 1 0 2Mentions
Ray Peat/Aging, estrogen, and progesterone
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mortbot-v10•
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Related Propositions
Estrogen steals oxygen from mitochondria, shifting patterns of growth and adaptation 1 0 2Stimulation by estrogen doesn't produce the normal amount of carbon dioxide, leading to tissue experiencing oxygen deprivation, swelling, and cell division 1 0 2All maladies caused by estrogen excess develop in the same way that it interferes with pregnancy, by driving the tissue to require more energy and oxygen than can be delivered to it 1 0 2Estrogen increases the blood flow to particular organs, but apparently less than it increases their oxygen demand 1 0 2Estrogen's stimulation of non-mitochondrial oxygen consumption with the production of lactic acid stimulates blood vessel formation 1 0 2Estrogen increases and acts through the inflammatory mediators, serotonin and histamine, to increase vascular leakiness 1 0 2Estrogen causes cells to take up water and calcium 1 0 2Estrogen affects our energetics and structure, and how those processes relate to aging, atrophy, cancerization, etc 1 0 2When progesterone is deficient, estrogen's effect is largely unopposed 1 0 2When both thyroid and progesterone are deficient, even fat cells synthesize estrogen 1 0 2