Collagen tends to accumulate with aging

Negation: Collagen does not tend to accumulate with aging 0 0 0

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1 Consequence

2 Mentions

Arguments

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Consequences

Argument #151de20d 1 0 2

If it is true that...

Estrogen is closely associated with the general loss of fat-free tissue with aging 1 0 2

and

Estrogen creates an oxygen deficiency, stimulates first swelling, and then collagen synthesis 1 0 2

and

Collagen tends to accumulate with aging 1 0 2

Then it must be true that...

Estrogen increases the blood flow to particular organs, but apparently less than it increases their oxygen demand 1 0 2

Mentions

Ray Peat/Aging, estrogen, and progesterone

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Related Propositions

In aging, tissues generally atrophy, with loss of both substance and activity 1 0 2 Certain effects of estrogen resemble changes seen in aging such as fibrotic changes of connective tissues, accelerated accumulation of age pigment, a tendency to miscarry, or the production of degenerative changes in various organs 1 0 2 Estrogen is closely associated with the general loss of fat-free tissue with aging 1 0 2 Estrogen creates an oxygen deficiency, stimulates first swelling, and then collagen synthesis 1 0 2 Protein synthesis declines with aging as the metabolic rate slows 1 0 2 In old age, the catabolic hormones such as cortisol are relatively dominant 1 0 2 Free fatty acids that are mobilized from storage tissues in the night and in the winter also tend to increase with aging as the ability to tolerate stress decreases 1 0 2 Iron accumulates to a point where its signal functions may be inappropriate during certain times, especially childhood and old age 1 0 2 The structure of the brain goes into an "entropic" deterioration during the process of aging 1 0 2 A vitamin A deficiency resembles stress and estrogen-toxicity aging 1 0 2