Protein synthesis declines with aging as the metabolic rate slows
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Ray Peat/Aging, estrogen, and progesterone
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Some hormones decrease with aging, while others increase 1 0 2In aging, tissues generally atrophy, with loss of both substance and activity 1 0 2Estrogen is closely associated with the general loss of fat-free tissue with aging 1 0 2In old age, the metabolic rate is decreased and sleep becomes defective 1 0 2In old age, the catabolic hormones such as cortisol are relatively dominant 1 0 2Interactions between estrogen and unsaturated fats contribute to the aging process 1 0 2In old age, the number of cells in the brain keeps increasing with age 1 0 2In the aged brain, glial cells multiply while neurons die 1 0 2The structure of the brain goes into an "entropic" deterioration during the process of aging 1 0 2The increased rate of metabolism, decreased free radical production, resistance to stress and poisoning by iron, alcohol, endotoxin, alloxan and streptozotocin, etc., improvement of brain structure and function, decreased susceptibility to blood clots, and lack of obesity and age pigment on a diet using coconut oil rather than unsaturated fats indicates that it is very likely acting by reducing the aging process itself at its physiological core 1 0 2