Estrogen increases and acts through the inflammatory mediators, serotonin and histamine, to increase vascular leakiness

Negation: Estrogen does not increase and act through the inflammatory mediators, serotonin and histamine, to increase vascular leakiness 0 0 0

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Argument #302b5fbb 1 0 2

If it is true that...

Estrogen increases and acts through the inflammatory mediators, serotonin and histamine, to increase vascular leakiness 1 0 2

and

Estrogen causes cells to take up water and calcium 1 0 2

and

The formation of lactic acid tends to coordinate these effects 1 0 2

Then it must be true that...

Hyperventilation is common in sleep and shock, sometimes producing extreme vasoconstriction due to the loss of carbon dioxide 1 0 2

Mentions

Ray Peat/Aging, estrogen, and progesterone

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Related Propositions

Serotonin, which is closely associated with estrogen, seems to be an important inducer of functionally suppressed states such as hibernation, social subordination, learned helplessness and depression 1 0 2 Estrogen creates an oxygen deficiency, stimulates first swelling, and then collagen synthesis 1 0 2 Estrogen increases the blood flow to particular organs, but apparently less than it increases their oxygen demand 1 0 2 Estrogen's stimulation of non-mitochondrial oxygen consumption with the production of lactic acid stimulates blood vessel formation 1 0 2 Estrogen causes cells to take up water and calcium 1 0 2 Estrogen sets the brain's temperature regulator lower but can also lower the metabolic rate through serotonin and other mediators 1 0 2 Estrogen affects our energetics and structure, and how those processes relate to aging, atrophy, cancerization, etc 1 0 2 Increased estrogen, nitric oxide, excitatory amino acids, cortisol, lactate, free unsaturated fatty acids, prolactin, growth hormone, histamine, serotonin, tumor necrosis factor and other pro-inflammatory cytokines and kinins, and a variety of prostaglandins and eicosanoids have been identified as anti-mitochondrial, anti-respiratory agents 1 0 2 Estrogen is intimately involved with the formation of the egg cell and wherever it operates, it increases both the quantity of water and the disorder of the water 1 0 2 Hypothyroidism, estrogen excess, free unsaturated fats cause increased vascular permeability and brain edema, protein leakage, and alteration of the matrix 1 0 2