Edema in the lungs limits oxygen absorption
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Ray Peat/Altitude and Morality
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Stimulation by estrogen doesn't produce the normal amount of carbon dioxide, leading to tissue experiencing oxygen deprivation, swelling, and cell division 1 0 2Estrogen creates an oxygen deficiency, stimulates first swelling, and then collagen synthesis 1 0 2An excessive nocturnal temperature drop probably increases edema, with all of its harmful consequences 1 0 2Breathing pure oxygen lowers the oxygen content of tissues 1 0 2Oxygen toxicity and hyperventilation create a systemic deficiency of carbon dioxide 1 0 2Carbon dioxide deficiency makes breathing more difficult in pure oxygen, impairs the heart’s ability to work, and increases the resistance of blood vessels, impairing circulation and oxygen delivery to tissues 1 0 2The loss of carbon dioxide from the lungs in the presence of high oxygen pressure increases the blood’s affinity for oxygen, and restricts its delivery to the tissues 1 0 2At high altitude, the slight tendency toward carbon dioxide-retention acidosis decreases the blood’s affinity for oxygen, making it more available to the tissues 1 0 2The lactic acid has to be disposed of, but their ability to extract oxygen is reduced 1 0 2Free fatty acids and lactate impair glucose use, and promote edema, especially in the lungs 1 0 2