Some people argued that aging was caused by hormonal deficiency
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Ray Peat/Aging, estrogen, and progesterone
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Some hormones decrease with aging, while others increase 1 0 2Unpleasant consequences of estrogen excess resemble some events of aging 1 0 2The absolute levels of estrogen, or the ratio of estrogen to the antiestrogens, increases with aging in a wide variety of organisms of both sexes, including humans 1 0 2Estrogen is closely associated with the general loss of fat-free tissue with aging 1 0 2In old age, the metabolic rate is decreased and sleep becomes defective 1 0 2In old age, the catabolic hormones such as cortisol are relatively dominant 1 0 2Changes of aging are also the result of complex interactions between organisms and their environment rather than some genetic program 1 0 2Stress, a "respiratory defect", and free radical damage are common factors in disease and aging 1 0 2Degenerative aging seems to be produced situationally, by various types of contamination of our energy supply 1 0 2A vitamin A deficiency resembles stress and estrogen-toxicity aging 1 0 2