The increased lipid peroxidation of old age represents a vicious circle, in which the loss of the antioxidants and vitamin A leads to their further destruction
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Stress, a "respiratory defect", and free radical damage are common factors in disease and aging 1 0 2Poor circulation and lipofuscin tend to be associated in a vicious cycle 1 0 1Interactions between estrogen and unsaturated fats contribute to the aging process 1 0 2Endotoxin poisoning eventually tends to intervene during stress and aging, exacerbating the trend begun under the influence of other factors 1 0 2Vitamin A promotes protein synthesis, regulates lysosomes, and protects against lipid peroxidation 1 0 1A vitamin A deficiency resembles stress and estrogen-toxicity aging 1 0 2The destruction of vitamin E by unsaturated fats leads to the destruction of vitamin A 1 0 2The mitochondrial energy problem, cytochrome oxidase and its regulation; body temperature/pulse-rate cycle disturbance; lipid peroxidation; respiratory defect; altered amino acid uptake; memory impairment; dominance of the excitatory systems vs. the inhibitory adenosine/GABA/progesterone/pregnenolone system are functional and biochemical observations of Alzheimer's disease 1 0 1Increased calcium uptake is associated with lipid peroxidation and cell death 1 0 1The increased rate of metabolism, decreased free radical production, resistance to stress and poisoning by iron, alcohol, endotoxin, alloxan and streptozotocin, etc., improvement of brain structure and function, decreased susceptibility to blood clots, and lack of obesity and age pigment on a diet using coconut oil rather than unsaturated fats indicates that it is very likely acting by reducing the aging process itself at its physiological core 1 0 2