Vitamin A functions as an estrogen antagonist in a variety of cell types
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Toxic effects of estrogens were known by the middle of the 20th century 1 0 2Unpleasant consequences of estrogen excess resemble some events of aging 1 0 2Estrogen steals oxygen from mitochondria, shifting patterns of growth and adaptation 1 0 2Estrogen's stimulation of non-mitochondrial oxygen consumption with the production of lactic acid stimulates blood vessel formation 1 0 2The electron transfer process of the mitochondria is interrupted by the futile redox cycling catalyzed by estrogens 1 0 2The toxicity of estrogen and unsaturated fats has been recognized for most of the twentieth century 1 0 2Interactions between estrogen and unsaturated fats contribute to the aging process 1 0 2Vitamin A promotes protein synthesis, regulates lysosomes, and protects against lipid peroxidation 1 0 1A vitamin A deficiency resembles stress and estrogen-toxicity aging 1 0 2The destruction of vitamin E by unsaturated fats leads to the destruction of vitamin A 1 0 2