Exposure to estrogen in middle-age does not increase the risk of Alzheimer's disease in old age
Negation: Exposure to estrogen in middle-age increases the risk of Alzheimer's disease in old age 1 0 2
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Toxic effects of estrogens were known by the middle of the 20th century 1 0 2Unpleasant consequences of estrogen excess resemble some events of aging 1 0 2Knowledge of how to protect against estrogen can be used to protect against aging 1 0 2The absolute levels of estrogen, or the ratio of estrogen to the antiestrogens, increases with aging in a wide variety of organisms of both sexes, including humans 1 0 2Estrogen is closely associated with the general loss of fat-free tissue with aging 1 0 2Interactions between estrogen and unsaturated fats contribute to the aging process 1 0 2Factors known to reduce brain size at birth are also involved in the degenerating brain in old age or Alzheimer's disease 1 0 2Exposure to estrogen in middle-age increases the risk of Alzheimer's disease in old age 1 0 2Even medical progestogens offer some protection against Alzheimer's disease 1 0 2Increased cortisol and DHEA are associated with Alzheimer's disease 1 0 1