Otto Warburg established that lactic acid production even in the presence of oxygen is a fundamental property of cancer
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Ray Peat/Altitude and Morality
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A cell emits lactic acid and free radicals when it isn't getting everything it needs, such as oxygen and glucose 1 0 2Estrogen's stimulation of non-mitochondrial oxygen consumption with the production of lactic acid stimulates blood vessel formation 1 0 2Breathing too much oxygen displaces too much carbon dioxide, provoking an increase in lactic acid 1 0 2Carbon dioxide inhibits the production of lactic acid, and lactic acid lowers carbon dioxide's concentration in a variety of ways 1 0 2The excess production of lactate displaces carbon dioxide from the blood, partly as a compensation for acidity 1 0 2The lactic acid has to be disposed of, but their ability to extract oxygen is reduced 1 0 2Lactic acid triggers the defensive reactions of the organism, leading to tissue wasting from excessive glucocorticoid hormone 1 0 2Free fatty acids and lactate impair glucose use, and promote edema, especially in the lungs 1 0 2The presence of lactic acid interferes with energy metabolism in ways that tend to be self-promoting 1 0 2Blocking the production of lactic acid can make cells more resistant 1 0 2