Lactic acid triggers the defensive reactions of the organism, leading to tissue wasting from excessive glucocorticoid hormone
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Ray Peat/Altitude and Morality
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A cell emits lactic acid and free radicals when it isn't getting everything it needs, such as oxygen and glucose 1 0 2The formation of lactic acid tends to coordinate these effects 1 0 2Breathing too much oxygen displaces too much carbon dioxide, provoking an increase in lactic acid 1 0 2The excess production of lactate displaces carbon dioxide from the blood, partly as a compensation for acidity 1 0 2Activity increases the need for oxygen, and also increases the tendency to accumulate lactic acid 1 0 2The lactic acid has to be disposed of, but their ability to extract oxygen is reduced 1 0 2Free fatty acids and lactate impair glucose use, and promote edema, especially in the lungs 1 0 2Increased estrogen, nitric oxide, excitatory amino acids, cortisol, lactate, free unsaturated fatty acids, prolactin, growth hormone, histamine, serotonin, tumor necrosis factor and other pro-inflammatory cytokines and kinins, and a variety of prostaglandins and eicosanoids have been identified as anti-mitochondrial, anti-respiratory agents 1 0 2The presence of lactic acid interferes with energy metabolism in ways that tend to be self-promoting 1 0 2Blocking the production of lactic acid can make cells more resistant 1 0 2