Polyunsaturated fats that accumulate in the brain and retina damage mitochondria

Negation: Polyunsaturated fats that accumulate in the brain and retina do not damage mitochondria 0 0 0

0 Arguments

0 Citations

1 Consequence

2 Mentions

Arguments

No arguments found

Opposing Arguments

No opposing arguments found

Citations

No citations found

Consequences

Argument #75e1db53 1 0 2

If it is true that...

Retinal injury is caused by ordinary light when the eyes are sensitized by melatonin, prolactin, and polyunsaturated fats 1 0 2

and

Melatonin and prolactin are induced by stress 1 0 2

and

Darkness is a stress because it impairs mitochondrial energy production 1 0 2

and

Polyunsaturated fats that accumulate in the brain and retina damage mitochondria 1 0 2

Then it must be true that...

Retinopathy of prematurity has blinded tens of thousands of people 1 0 2

Mentions

Ray Peat/Aging Eyes, Infant Eyes, and Excitable Tissues

Maintained by

0•

Updated

Related Propositions

Retinal injury is caused by ordinary light when the eyes are sensitized by melatonin, prolactin, and polyunsaturated fats 1 0 2 Light and stress, especially with excess iron, damage the retina when the cells contain too much PUFA 1 0 2 Mitochondrial function in general is poisoned by the unsaturated fats, especially arachidonic acid and DHA 1 0 2 Creating a "deficiency" of DHA prevents retinal damage from light 1 0 2 When animals are made "deficient" in all the exogenous polyunsaturated fatty acids, they become remarkably resistant to all sorts of stress and toxins 1 0 2 The polyunsaturated fats make the lungs more sensitive to excess oxygen or hyperventilation, they make the eyes more sensitive to light, and they make the brain more sensitive to fatigue 1 0 2 Excessive supply of unsaturated fats in the diet can override some adaptive, protective regulatory processes 1 0 2 Lipid peroxidation damages the mitochondrias' ability to produce pregnenolone 1 0 2 Hypothyroidism, estrogen excess, free unsaturated fats cause increased vascular permeability and brain edema, protein leakage, and alteration of the matrix 1 0 2 An excess of unsaturated fatty acids constitutes a massive distortion of the regulatory systems 1 0 2