Not all maladies caused by estrogen excess develop in the same way that it interferes with pregnancy, by driving the tissue to require more energy and oxygen than can be delivered to it
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Estrogen can cause cancer, abnormal blood clotting, and infertility 1 0 2Unpleasant consequences of estrogen excess resemble some events of aging 1 0 2Estrogen steals oxygen from mitochondria, shifting patterns of growth and adaptation 1 0 2Stimulation by estrogen doesn't produce the normal amount of carbon dioxide, leading to tissue experiencing oxygen deprivation, swelling, and cell division 1 0 2Certain effects of estrogen resemble changes seen in aging such as fibrotic changes of connective tissues, accelerated accumulation of age pigment, a tendency to miscarry, or the production of degenerative changes in various organs 1 0 2All maladies caused by estrogen excess develop in the same way that it interferes with pregnancy, by driving the tissue to require more energy and oxygen than can be delivered to it 1 0 2Estrogen creates an oxygen deficiency, stimulates first swelling, and then collagen synthesis 1 0 2Estrogen increases the blood flow to particular organs, but apparently less than it increases their oxygen demand 1 0 2Estrogen affects our energetics and structure, and how those processes relate to aging, atrophy, cancerization, etc 1 0 2Estrogen is intimately involved with the formation of the egg cell and wherever it operates, it increases both the quantity of water and the disorder of the water 1 0 2