The pituitary hormones, especially prolactin and TSH, are pro-inflammatory
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Darkness creates an inflammatory state 1 0 2Estrogen increases and acts through the inflammatory mediators, serotonin and histamine, to increase vascular leakiness 1 0 2Melatonin and prolactin are induced by stress 1 0 2Prolactin is sometimes elevated in the newborn 1 0 2The nocturnal/stress hormones, especially prolactin and melatonin, make the retina more sensitive to light and more easily damaged 1 0 2Darkness increases TSH along with prolactin 1 0 1Endotoxin impairs mitochondria, increases estrogen levels, causes Kupffer cells in the liver to produce more tumor necrosis factor 1 0 2Increased estrogen, nitric oxide, excitatory amino acids, cortisol, lactate, free unsaturated fatty acids, prolactin, growth hormone, histamine, serotonin, tumor necrosis factor and other pro-inflammatory cytokines and kinins, and a variety of prostaglandins and eicosanoids have been identified as anti-mitochondrial, anti-respiratory agents 1 0 2Thyroid, progesterone, magnesium, glucose, and saturated fatty acids are among the central protective elements 1 0 2The potential hormone-like action of everything in the body should be considered 1 0 2