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Cytochrome oxidase is not one of the enzymes damaged by stress and by blue light, and not activated or restored by red light, thyroid, and progesterone

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The electron transfer process of the mitochondria is interrupted by the futile redox cycling catalyzed by estrogens 1 0 2Retinal injury is caused by ordinary light when the eyes are sensitized by melatonin, prolactin, and polyunsaturated fats 1 0 2Darkness is a stress because it impairs mitochondrial energy production 1 0 2Stress, a "respiratory defect", and free radical damage are common factors in disease and aging 1 0 2The absence of bright light can create a progesterone deficiency and leave estrogen and prolactin unopposed 1 0 2Light and stress, especially with excess iron, damage the retina when the cells contain too much PUFA 1 0 2Cytochrome oxidase is one of the enzymes damaged by stress and by blue light, and activated or restored by red light, thyroid, and progesterone 1 0 2Progesterone and pregnenolone, by reducing the stress reactions, should be helpful in the eye diseases of infancy and old age, as they are in the respiratory distress syndromes 1 0 1Increased estrogen, nitric oxide, excitatory amino acids, cortisol, lactate, free unsaturated fatty acids, prolactin, growth hormone, histamine, serotonin, tumor necrosis factor and other pro-inflammatory cytokines and kinins, and a variety of prostaglandins and eicosanoids have been identified as anti-mitochondrial, anti-respiratory agents 1 0 2The mitochondrial energy problem, cytochrome oxidase and its regulation; body temperature/pulse-rate cycle disturbance; lipid peroxidation; respiratory defect; altered amino acid uptake; memory impairment; dominance of the excitatory systems vs. the inhibitory adenosine/GABA/progesterone/pregnenolone system are functional and biochemical observations of Alzheimer's disease 1 0 1