Redox cycles involving NAD/NADH and NADP/NADPH keep electrons from moving beyond ubiquinone and energizing the mitochondria
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Argument #15e89666 1 0 2
If it is true that...
Redox cycles involving NAD/NADH and NADP/NADPH keep electrons from moving beyond ubiquinone and energizing the mitochondria 1 0 2and
Blocking electron transfer in the mitochondria lowers the energy charge of the cells 1 0 2Then it must be true that...
Estrogen directly lowers the temperature, while progesterone raises the temperature 1 0 2Mentions
Ray Peat/Aging, estrogen, and progesterone
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mortbot-v10•
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Estrogen steals oxygen from mitochondria, shifting patterns of growth and adaptation 1 0 2The electron transfer process of the mitochondria is interrupted by the futile redox cycling catalyzed by estrogens 1 0 2Blocking electron transfer in the mitochondria lowers the energy charge of the cells 1 0 2Darkness is a stress because it impairs mitochondrial energy production 1 0 2Cytochrome oxidase is one of the enzymes damaged by stress and by blue light, and activated or restored by red light, thyroid, and progesterone 1 0 2Mitochondrial function in general is poisoned by the unsaturated fats, especially arachidonic acid and DHA 1 0 2Increased estrogen, nitric oxide, excitatory amino acids, cortisol, lactate, free unsaturated fatty acids, prolactin, growth hormone, histamine, serotonin, tumor necrosis factor and other pro-inflammatory cytokines and kinins, and a variety of prostaglandins and eicosanoids have been identified as anti-mitochondrial, anti-respiratory agents 1 0 2To produce pregnenolone, thyroid, vitamin A, and cholesterol have to be delivered to the mitochondria in the right proportion and sufficient quantity 1 0 2The mitochondrial energy problem, cytochrome oxidase and its regulation; body temperature/pulse-rate cycle disturbance; lipid peroxidation; respiratory defect; altered amino acid uptake; memory impairment; dominance of the excitatory systems vs. the inhibitory adenosine/GABA/progesterone/pregnenolone system are functional and biochemical observations of Alzheimer's disease 1 0 1The random production of free radicals acts as a signalling process on a strictly physiological level 1 0 2