Estrogen and acetylcholine are excitotoxins
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Many chemicals can produce effects similar to estrogen 1 0 1Toxic effects of estrogens were known by the middle of the 20th century 1 0 2Unpleasant consequences of estrogen excess resemble some events of aging 1 0 2Estrogen steals oxygen from mitochondria, shifting patterns of growth and adaptation 1 0 2Many toxic chemicals and stressful physical processes can activate the same functions as estrogen 1 0 2Estrogen affects our energetics and structure, and how those processes relate to aging, atrophy, cancerization, etc 1 0 2Increased estrogen, nitric oxide, excitatory amino acids, cortisol, lactate, free unsaturated fatty acids, prolactin, growth hormone, histamine, serotonin, tumor necrosis factor and other pro-inflammatory cytokines and kinins, and a variety of prostaglandins and eicosanoids have been identified as anti-mitochondrial, anti-respiratory agents 1 0 2The toxicity of estrogen and unsaturated fats has been recognized for most of the twentieth century 1 0 2Exposure to estrogen in middle-age increases the risk of Alzheimer's disease in old age 1 0 2Estrogen is a brain excitant, present use creates an effect on verbal fluency and other signs of awareness of the environment 1 0 2