Formation of prostaglandins, prostacyclin, and thromboxane is not blocked by aspirin and other anti-inflammatory drugs
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Estrogen increases and acts through the inflammatory mediators, serotonin and histamine, to increase vascular leakiness 1 0 2When animals are made "deficient" in all the exogenous polyunsaturated fatty acids, they become remarkably resistant to all sorts of stress and toxins 1 0 2Aspirin is generally protective to the retina 1 0 1Increased estrogen, nitric oxide, excitatory amino acids, cortisol, lactate, free unsaturated fatty acids, prolactin, growth hormone, histamine, serotonin, tumor necrosis factor and other pro-inflammatory cytokines and kinins, and a variety of prostaglandins and eicosanoids have been identified as anti-mitochondrial, anti-respiratory agents 1 0 2Inflammation and blood clots may be factors in the aging brain 1 0 2Dietary changes can drastically reduce the toxicity of linoleic acid, linolenic acid, and arachidonic acid 1 0 2Formation of prostaglandins, prostacyclin, and thromboxane is blocked by aspirin and other anti-inflammatory drugs 1 0 2Aspirin protects against iron toxicity, clot formation, and reduces lipid peroxidation while blocking prostaglandin formation 1 0 2Mead acids do not activate cell systems in the same way that plant-derived PUFAs do 1 0 1Mead acids are the precursors for an entirely different group of prostaglandins 1 0 2