Ascending less than or equal to 200 feet per day does not produce measurable stress
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An excessive nocturnal temperature drop probably increases edema, with all of its harmful consequences 1 0 2Darkness is a stress because it impairs mitochondrial energy production 1 0 2Stress, a "respiratory defect", and free radical damage are common factors in disease and aging 1 0 2Almost any kind of stress increases the formation of melatonin 1 0 2Free fatty acids that are mobilized from storage tissues in the night and in the winter also tend to increase with aging as the ability to tolerate stress decreases 1 0 2Melatonin's ability to cause vasoconstriction means that stress makes supplemental oxygen more toxic 1 0 1Mountain sickness develops in some people when they ascend too rapidly to a high altitude 1 0 2Periods of higher pressure correspond to an increased incidence of death from heart disease and strokes 1 0 1Ascending more than 200 feet per day produces measurable stress 1 0 2Stress is normally balanced by increased synthesis of pregnenolone, which improves the ability to cope with stress 1 0 2