Serotonin, which is closely associated with estrogen, does not seem to be an important inducer of functionally suppressed states such as hibernation, social subordination, learned helplessness and depression
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Serotonin, which is closely associated with estrogen, seems to be an important inducer of functionally suppressed states such as hibernation, social subordination, learned helplessness and depression 1 0 2The absolute levels of estrogen, or the ratio of estrogen to the antiestrogens, increases with aging in a wide variety of organisms of both sexes, including humans 1 0 2Estrogen increases and acts through the inflammatory mediators, serotonin and histamine, to increase vascular leakiness 1 0 2Estrogen sets the brain's temperature regulator lower but can also lower the metabolic rate through serotonin and other mediators 1 0 2Estrogen plays a role in organisms as diverse as yeasts, worms, mollusks, and in modifying the function of practically every type of animal cell--skin, nerve, muscle, bone, hair, gland, etc 1 0 2Many toxic chemicals and stressful physical processes can activate the same functions as estrogen 1 0 2Estrogen affects our energetics and structure, and how those processes relate to aging, atrophy, cancerization, etc 1 0 2Estrogen and unsaturated fats can interact in ways that change restraint and adaptation into sudden self-destruction 1 0 2Estrogen is a brain excitant, present use creates an effect on verbal fluency and other signs of awareness of the environment 1 0 2Endorphins are stress-induced and involved in estrogen action 1 0 1