If it is true that...

The process of figuring out what to work on can be complicated and requires experience in the field

and

Ambition can make it difficult to decide what to work on

Then it must be true that...

Fear and modesty prevent many people from attempting great work

If it is true that...

There are numerous ways to do great work

and

Fear and modesty prevent many people from attempting great work

Then it must be true that...

Great work involves expanding people's ideas of what's possible

If it is true that...

Pretentiousness, fashion, fear, money, politics, and other people's wishes can lead one astray when trying to figure out what to work on

and

Fear and modesty prevent many people from attempting great work

Then it must be true that...

Great work involves expanding people's ideas of what's possible

If it is true that...

Fear and modesty prevent many people from attempting great work

and

Great work involves expanding people's ideas of what's possible

Then it must be true that...

The importance of a task is often hard to judge at the time it is done