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79 propositions
70 inferences
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Claim
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
Arguments
If it is true that...
Interactions between estrogen and unsaturated fats contribute to the aging process
and
Exposure to estrogen in middle-age increases the risk of Alzheimer's disease in old age
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
If it is true that...
Aspirin protects against iron toxicity, clot formation, and reduces lipid peroxidation while blocking prostaglandin formation
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
If it is true that...
Vegetable oil suppresses the thyroid, increasing estrogen
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
If it is true that...
If rats are treated during pregnancy to increase the amount of progesterone, the offspring have bigger brains and learn more efficiently
and
Progesterone is a nerve growth factor, produced by glial cells
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
If it is true that...
Estrogen is a brain excitant, present use creates an effect on verbal fluency and other signs of awareness of the environment
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
If it is true that...
Exposure to estrogen in middle-age increases the risk of Alzheimer's disease in old age
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
If it is true that...
Free radicals and calcium cause multiple cell injuries including nerve-death
and
Estrogen is released by elevated beta-glucuronidase
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
If it is true that...
Imbalances of other steroids, including cortisol and DHEA, develop as cells compensate for pregnenolone deficiency
and
Hypothyroidism, estrogen excess, free unsaturated fats cause increased vascular permeability and brain edema, protein leakage, and alteration of the matrix
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
If it is true that...
When progesterone is deficient, estrogen's effect is largely unopposed
and
When both thyroid and progesterone are deficient, even fat cells synthesize estrogen
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
If it is true that...
Transthyretin and apo E accumulate unused, and deposit in blood vessels, around nerves, and in cytoplasm when microtubule transport is disrupted
and
Pregnenolone and progesterone deficiency causes memory loss, destabilization of nerve cells, failure of myelin formation, and excess cortisol synthesis
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
If it is true that...
Even medical progestogens offer some protection against Alzheimer's disease
Then it must be true that...
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
Consequences
If it is true that...
Estrogen is a brain excitant, present use creates an effect on verbal fluency and other signs of awareness of the environment
and
Alzheimer-type dementia is different from other dementias, but it overlaps with them, and with age-related and stress-related changes in other organs
Then it must be true that...
Imbalances of other steroids, including cortisol and DHEA, develop as cells compensate for pregnenolone deficiency