If it is true that...

To produce pregnenolone, thyroid, vitamin A, and cholesterol have to be delivered to the mitochondria in the right proportion and sufficient quantity

and

Lipid peroxidation damages the mitochondrias' ability to produce pregnenolone

Then it must be true that...

When pregnenolone is inadequate, cortisol is over-produced

If it is true that...

Lipid peroxidation damages the mitochondrias' ability to produce pregnenolone

Then it must be true that...

When pregnenolone is inadequate, cortisol is over-produced

If it is true that...

When pregnenolone is inadequate, cortisol is over-produced

Then it must be true that...

When progesterone is deficient, estrogen's effect is largely unopposed