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41 propositions
32 inferences
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Claim
Retinopathy of prematurity has blinded tens of thousands of people
Arguments
If it is true that...
Premature babies are often given extra oxygen, which tends to cause vasoconstriction by displacing carbon dioxide
and
Supplemental oxygen without carbon dioxide causes vasoconstriction, reducing the tissues' supply of glucose as well as oxygen and damages the retina when combined with too much light
Then it must be true that...
Retinopathy of prematurity has blinded tens of thousands of people
If it is true that...
Synthetic glucocorticoids are often given to premature babies, adding to the risk of retinal damage
and
The use of synthetic glucocorticoid hormone is standard in treating very premature babies although it is known to contribute to eye damage
Then it must be true that...
Retinopathy of prematurity has blinded tens of thousands of people
If it is true that...
Supplemental oxygen without carbon dioxide causes vasoconstriction, reducing the tissues' supply of glucose as well as oxygen and damages the retina when combined with too much light
and
Bright light contributes to retinal damage in babies
Then it must be true that...
Retinopathy of prematurity has blinded tens of thousands of people
If it is true that...
Retinal injury is caused by ordinary light when the eyes are sensitized by melatonin, prolactin, and polyunsaturated fats
and
Melatonin and prolactin are induced by stress
and
Darkness is a stress because it impairs mitochondrial energy production
and
Polyunsaturated fats that accumulate in the brain and retina damage mitochondria
Then it must be true that...
Retinopathy of prematurity has blinded tens of thousands of people
If it is true that...
The fetus accumulates a very large amount of iron and absorbs melatonin from the maternal circulation
and
Prolactin is sometimes elevated in the newborn
and
Premature babies are often given extra oxygen, which tends to cause vasoconstriction by displacing carbon dioxide
and
Synthetic glucocorticoids are often given to premature babies, adding to the risk of retinal damage
Then it must be true that...
Retinopathy of prematurity has blinded tens of thousands of people
If it is true that...
Light and stress, especially with excess iron, damage the retina when the cells contain too much PUFA
Then it must be true that...
Retinopathy of prematurity has blinded tens of thousands of people
If it is true that...
The use of synthetic glucocorticoid hormone is standard in treating very premature babies although it is known to contribute to eye damage
and
Cortisol-like drugs damage the brain and other organs
Then it must be true that...
Retinopathy of prematurity has blinded tens of thousands of people
If it is true that...
Iron supplements and supplemental oxygen can do the most damage when used with a vitamin E deficiency exacerbated by excessive unsaturated fats in the diet
Then it must be true that...
Retinopathy of prematurity has blinded tens of thousands of people