If it is true that...

Estrogen sets the brain's temperature regulator lower but can also lower the metabolic rate through serotonin and other mediators

and

Estrogen plays a role in organisms as diverse as yeasts, worms, mollusks, and in modifying the function of practically every type of animal cell--skin, nerve, muscle, bone, hair, gland, etc

Then it must be true that...

Many toxic chemicals and stressful physical processes can activate the same functions as estrogen